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Evaluating the Impact and Practicality of a National Digital Intervention for Type 2 Diabetes Mellitus: Single-Arm Nonrandomized Pilot Trial
Managing type 2 diabetes usually means ongoing lifestyle changes, which can be hard to keep up without regular support. This single-arm, nonrandomized pilot trial aimed to assess the real-world impact and feasibility of a national digital intervention combining remote health coaching, structured digital education, and self-monitoring via WhatsApp over a 16-week period. The findings revealed meaningful improvements in participants' blood sugar levels, weight, cholesterol, and overall quality of life — with most sticking with the program all the way through and reporting high satisfaction. The pilot trial demonstrated the acceptability, preliminary effectiveness, and feasibility for individuals with type 2 diabetes in Brunei.
An Innovative Population Health Tool for Overall Health Status Assessment- Prospective Observational Study
Chronic illnesses like diabetes and heart disease make up the majority of deaths in Brunei, and many of the risk factors behind them can be changed with the right support. This study aimed to find out whether a self-assessment tool could help people understand their own health status and catch early warning signs before they turn into serious illness. "Health Index", available in BruHealth, consists of a set of questions covering everyday lifestyle habits that tells users whether they're healthy, at-risk, or in poor health, along with tips on what to improve. Most people who used the tool were found to be at-risk, and unhealthy eating habits stood out as the biggest concern. The findings suggest the tool could potentially enable early detection and management of non-communicable disease risk factors to mitigate the high cost of advanced disease and complications.
Technology-assisted adaptive recruitment strategy for a large nation-wide COVID-19 vaccine immunogenicity study in Brunei
The Bruneian study evaluated the effectiveness of various COVID-19 vaccine brands and aimed to understand how well these vaccines worked to protect people against COVID-19 by examining antibodies. Over five weeks, 2,712 participants were recruited to be part of the study. EVYDResearch, our dedicated research platform, was used to select participants based on age, gender, and vaccine type. Our digital tools helped gather data quickly and adaptive approaches to recruitment were used to improve participation rates.
Immunogenicity of COVID-19 vaccines and levels of SARS-CoV-2 neutralizing antibody in the Bruneian population: Protocol for a national longitudinal study
Neutralising antibodies (NAbs) have been shown to be correlated to immune protection against SARS-CoV-2. This paper reports the protocol for a national longitudinal study to assess and compare the level of NAbs generated in response to COVID-19 vaccines in Brunei Darussalam in adults 2-6 weeks post-primary series (BBIBP-CorV, AZD1222, or mRNA-1273 vaccines) and their subsequent follow-up after administration of a third (booster-1) dose (BBIBP-CorV, mRNA-1273, or BNT162b2).
Development and Exploration of the Effectiveness and Feasibility of a Digital Intervention for Type 2 Diabetes Mellitus (DEsireD): Protocol for a Clinical Nonrandomised Pilot Trial in Brunei Darussalam
The prevalence of type 2 diabetes mellitus (T2DM) is increasing worldwide. Digital interventions that incorporate the use of mobile phones and wearables are gaining in popularity. A combination of a digital intervention with support from professional management can enhance users' self-efficacy better than digital intervention alone and provide better accessibility to lifestyle interventions. However, there are limited studies exploring the feasibility and efficacy of applying a digital intervention in Muslim-majority countries, and none have been conducted in Brunei Darussalam. The study aimed to determine the effectiveness and feasibility of a proposed 16-week digital intervention program for T2DM self-management and to guide the rollout of a mobile app as part of a population health solution for adults with T2DM in Brunei.
